Filter Media: Regenerated Cellulose Memebrane
Dia: 13mm, 25mm, 33mm, 50mm
Pore Size: 0.22μm, 0.45μm
Availability: In Stock
Regenerated Cellulose (RC) Syringe Filters – Sterile & Non-Sterile
Description
Hydrophilic Low Binding Filtration for Aqueous & Sensitive Samples
Hawach regenerated cellulose (RC) syringe filters are hydrophilic, low protein binding membrane filters designed for aqueous solutions, biological samples, and sensitive analytical applications. Compared with general filtration membranes, RC filters provide ultra-low protein adsorption for high sample recovery, hydrophilic structure for direct water-based filtration, very low extractables for clean analytical results, stable flow performance for routine lab workflows, and sterile/non-sterile options for different applications.
Ideal for HPLC aqueous sample prep, biological fluids, and sensitive laboratory filtration.
Recommended Choice for Sensitive Aqueous & Biological Samples
0.22 µm Sterile RC Syringe Filter
- Ultra-low protein binding membrane – high recovery of antibodies, enzymes, and growth factors
- Gamma sterilized (SAL 10⁻⁶) – ready-to-use for aseptic workflows
- Very low extractables – clean HPLC baselines
- High recovery for biological molecules – validated low adsorption
Best choice for cell culture media, protein solutions, and sterile aqueous filtration
Quick Selection Guide (3-Second Decision)
| Use Case | Recommended Series | Pore Size |
| Sterile biological filtration | Sterile RC | 0.22 µm |
| Protein / enzyme sample prep | Sterile RC | 0.22 µm |
| General aqueous clarification | Standard RC | 0.45 µm |
| Pre-analysis sample filtration (HPLC) | Standard or Sterile RC | 0.22–0.45 µm |
| Gas / air venting | RC Vent Filter | 0.22–0.45 µm |
Applications
Regenerated cellulose syringe filters are widely used in:
- HPLC / UHPLC aqueous sample preparation
- Protein and enzyme solution filtration
- Biological fluid clarification
- Cell culture media filtration
- Pharmaceutical aqueous QC testing
- Environmental water analysis
- General laboratory sample preparation
Product Configuration Options
| Type | Sterility | Positioning | Application |
| Standard RC | Non-sterile | Analytical grade | Routine aqueous filtration |
| Sterile RC | Gamma sterile | Bio/pharma grade | Cell culture & microbiology |
| RC Vent Filter | Sterile | Gas/air filtration | Sterile venting applications |
Key Features
- Hydrophilic membrane – no pre-wetting required, direct aqueous filtration
- Ultra-low protein binding – high recovery of biomolecules (validated >95% for BSA)
- Very low extractables – clean chromatographic results (HPLC certified)
- Fast flow rate – efficient sample processing
- Broad aqueous compatibility – ideal for water-based solutions
- Sterile option available – gamma irradiation (SAL 10⁻⁶)
- Low endotoxin – < 0.25 EU/mL (sterile series)
Technical Specifications
| Parameter | Specification |
| Membrane Material | Regenerated Cellulose (RC) |
| Type | Hydrophilic |
| Pore Sizes | 0.22 / 0.45 µm |
| Diameters | 13 / 25 / 33 / 50 mm |
| Housing | Medical-grade polypropylene (PP) |
| Max Operating Pressure | ≤ 5.2 bar (approx. 75 psi) |
| Temperature Range | Up to 60°C |
| Sterility (Sterile Series) | Gamma irradiation (SAL 10⁻⁶) |
| Endotoxin Level | < 0.25 EU/mL (sterile series) |
| Protein Binding | Very low (validated for BSA, IgG) |
| Extractables | Ultra-low extractables for clean chromatographic results (210–254 nm) |
Detailed SKU & Ordering Information
Most popular for labs: 11108403 / 11108405 (0.22 µm sterile)
Sterile Regenerated Cellulose Syringe Filters (Pharma & Biotech Grade)
| Item Code | Pore Size(µm) | Diameter(mm) | Sterile | Quantity/pk |
| 11108403 | 0.22 | 100 | Gamma sterile | 100 |
| 11108404 | 0.45 | 100 | Gamma sterile | 100 |
| 11108405 | 0.22 | 100 | Gamma sterile | 100 |
| 11108406 | 0.45 | 100 | Gamma sterile | 100 |
| 11108407 | 0.22 | 50 | Gamma sterile | 50 |
| 11108408 | 0.45 | 50 | Gamma sterile | 50 |
| 11108409 | 0.22 | 25 | Gamma sterile | 25 |
| 11108410 | 0.45 | 25 | Gamma sterile | 25 |
RC Vent Filters (Non-Sterile, for Gas/Air Venting)
| Item Code | Pore Size(µm) | Diameter(mm) | Sterile | Quantity/pk |
| 11104203 | 0.22 | 13 | NO | 100 |
| 11104204 | 0.45 | 13 | NO | 100 |
| 11104205 | 0.22 | 25 | NO | 100 |
| 11104008 | 0.45 | 25 | NO | 100 |
| 11104207 | 0.22 | 33 | NO | 50 |
| 11104208 | 0.45 | 33 | NO | 50 |
| 11104209 | 0.22 | 50 | NO | 25 |
| 11104210 | 0.45 | 50 | NO | 25 |
Custom options: Other diameters (4 mm, 50 mm) and pore sizes available upon request. Contact sales for OEM and private label.
RC vs Other Membrane Filters
| Membrane | Strength | Best Use | Limitation |
| RC | Ultra-low binding, low extractables | Sensitive aqueous & biological samples | Not for organic solvents |
| CA | Low protein binding | General biological filtration | Not for solvents |
| PES | Very high performance, ultra-low binding | Protein/biotech applications | Not for solvents |
| PTFE | Chemical resistance | Organic solvents, gases | Requires pre-wetting for water |
For general biological filtration – CA Syringe Filters
For ultra-low protein binding workflows – PES Syringe Filters
For solvent filtration – PTFE Syringe Filters
Why Choose Hawach RC Syringe Filters?
| Feature | Benefit |
| Ultra-low protein adsorption | Maximizes recovery of precious proteins and enzymes |
| Low extractables (HPLC certified) | Clean chromatographic baselines, no ghost peaks |
| High recovery for biological samples | Validated >95% for model proteins |
| Hydrophilic, no pre-wetting | Direct use for aqueous solutions – saves time |
| Sterile options (gamma irradiated) | Ready for cell culture and aseptic processing |
| CE / 9001 certified | Batch-to-batch consistency and traceability |
Quality & Manufacturing Assurance
- CE& ISO 9001 certified production
- ISO Class 7 cleanroom for sterile series manufacturing
- Gamma sterilization – Sterility Assurance Level (SAL) 10⁻⁶
- Endotoxin tested – < 0.25 EU/mL (sterile series)
- Low extractables validated – by HPLC (210–254 nm)
- Protein binding validated – typical recovery > 95% for BSA and IgG
- Batch traceability – each lot tested for integrity and performance
- 100% integrity testing – no leakage or membrane defects
Frequently Asked Questions (FAQ)
What is regenerated cellulose syringe filter used for?
It is used for aqueous and biological sample filtration, especially protein, enzyme, and cell culture media preparation, as well as HPLC sample prep where low extractables are critical.
Is RC membrane low protein binding?
Yes, RC has very low protein adsorption (validated >95% recovery) and is ideal for high-recovery applications.
Can RC filters be used for organic solvents?
No. RC is designed for aqueous solutions only. For organic solvents, use PTFE syringe filters.
What pore size is used for sterile filtration?
0.22 µm is the standard for sterile filtration and bacterial removal (SAL 10⁻⁶).
What is an RC vent filter used for?
It is used for sterile gas and air venting applications (e.g., bioreactor inlet/outlet, sterile container vents).
What is the difference between RC and CA/PES filters?
- RC: Ultra-low protein binding + very low extractables – best for HPLC and sensitive biomolecule recovery.
- CA: Low protein binding, cost-effective, general biological use.
- PES: High flow, ultra-low binding, ideal for high-throughput protein filtration.
Can RC filters be autoclaved?
No, they are single-use. Sterile versions are gamma irradiated; do not autoclave.
Ordering & Customization
Hawach RC syringe filters are available in multiple pore sizes (0.22, 0.45 µm), diameters (13–50 mm), and sterility configurations. We support:
- OEM / private label customization (logo, packaging, SKU)
- Bulk supply for distributors and large laboratories
- Fast global delivery from stock
- Free samples for qualified customers
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