Organic Solvent Filtration | HPLC Mobile Phase | Gas Venting
Drop-in Replacement: Millipore, Whatman, Advantec
Also available: Custom rolls & OEM supply
Availability: In Stock
PTFE Membrane Filter | 0.1-5.0 μm
Description
Why Labs & Procurement Choose Hawach
- Industry-Standard Membrane: HPLC / LC-MS mobile phase filtration, gas venting, aggressive organic solvents.
- Inherently Hydrophobic: No surfactant coating → zero contamination risk.
- Low Extractable: Protects sensitive analytical baselines, reduces ghost peaks.
- Extreme Chemical Resistance: Stable pH 1–14, compatible with strong acids, bases, and solvents.
- High Flow & Sterilization Compatible: Optimized pore network, autoclave & gamma irradiation safe.
- Procurement Advantages: Direct replacement for Millipore, Whatman, Advantec; OEM & bulk options available; batch-to-batch pore consistency.
Recognized as direct replacement for top lab brands in analytical and industrial solvent filtration.
What is PTFE Membrane?
Polytetrafluoroethylene (PTFE) membrane is a premium fluoropolymer filtration material with:
- Inherent chemical inertness – resists most lab solvents, strong acids & bases
- Natural hydrophobicity – water repellent, no surfactant coating
- Thermal stability – continuous use up to 130°C, fully autoclavable
- Low extractable composition – ideal for HPLC, LC-MS, trace analysis
Two categories: Hydrophobic (organic solvents & gas) and Hydrophilic (aqueous & biological samples). Hawach hydrophobic PTFE retains the native non-wettable structure, eliminating coating-related contamination risks.
Selection Algorithm – Which Membrane Fits Your Workflow?
| Workflow Involves | Recommended Membrane | Reason |
| Organic solvents (ACN, MeOH, THF, hexane) | Hydrophobic PTFE | Industry standard for non-aqueous filtration |
| Aqueous buffers & biological samples | Hydrophilic PTFE / PES / Nylon | Natural water penetration |
| HPLC / LC-MS mobile phase prep | 0.22 μm Low Extractable PTFE | Minimizes ghost peaks & protects columns |
| Gas venting & sterile air filtration | 0.22–0.45 μm Hydrophobic PTFE | High airflow with liquid barrier |
| Aggressive strong acid / base filtration | Hydrophobic PTFE | Maximum chemical inertness |
10-Second Pore Size Guide
| Application | Recommended Pore Size | Benefit |
| HPLC mobile phase filtration | 0.22 μm | Fine particle removal, column protection |
| General organic solvent filtration | 0.45 μm | Balanced flow & retention |
| Gas venting / sterile air | 0.22–0.45 μm | High airflow, reliable liquid barrier |
| Viscous solvents / prefiltration | 1.0–5.0 μm | High throughput & less clogging |
Hydrophobic vs Hydrophilic PTFE
| Property | Hydrophobic PTFE | Hydrophilic PTFE |
| Water filtration | Not suitable | Compatible |
| Organic solvent performance | Excellent | Limited |
| Gas venting | Ideal | Not preferred |
| HPLC mobile phase | Standard choice | Limited application |
| Pre-wetting required | No | Usually required |
Why PTFE Over Nylon, PES, PVDF?
| Membrane | Solvent Resistance | Natural Hydrophobic | Best Use Case |
| PTFE | Excellent | Yes | Organic solvents, HPLC, gas venting |
| Nylon | Moderate | No | General aqueous filtration |
| PES | Limited | No | Biological aqueous samples |
| PVDF | Good | Optional | Protein & biomolecular applications |
Core Technical Specifications
| Parameter | Specification |
| Material | Natural hydrophobic PTFE |
| Pore Sizes | 0.1 / 0.22 / 0.45 / 5.0 μm |
| Diameter Range | 13 / 25 / 47 / 50 / 60 / 90 / 142 mm |
| Wettability | Non-wettable / hydrophobic |
| Extractables | Low – HPLC & LC-MS grade |
| pH Compatibility | 1–14 |
| Max Continuous Temp | 130°C |
| Sterilization | Autoclavable, Gamma irradiation compatible |
Scanning Electron Microscope Picture
Ordering Information – Full SKU List
0.1 μm pore size
| SKU | Diameter | Pack Quantity |
| 11147101 | 13 mm | 400 pcs/pk |
| 11147103 | 25 mm | 200 pcs/pk |
| 11147104 | 47 mm | 100 pcs/pk |
| 11147105 | 50 mm | 100 pcs/pk |
| 11147106 | 60 mm | 50 pcs/pk |
| 11147107 | 90 mm | 50 pcs/pk |
| 11147110 | 142 mm | 50 pcs/pk |
0.22 μm pore size
| SKU | Diameter | Pack Quantity |
| 11147114 | 13 mm | 400 pcs/pk |
| 11147116 | 25 mm | 200 pcs/pk |
| 11147117 | 47 mm | 100 pcs/pk |
| 11147118 | 50 mm | 100 pcs/pk |
| 11147119 | 60 mm | 50 pcs/pk |
| 11147120 | 90 mm | 50 pcs/pk |
| 11147123 | 142 mm | 50 pcs/pk |
0.45 μm pore size
| SKU | Diameter | Pack Quantity |
| 11147127 | 13 mm | 400 pcs/pk |
| 11147129 | 25 mm | 200 pcs/pk |
| 11147130 | 47 mm | 100 pcs/pk |
| 11147131 | 50 mm | 100 pcs/pk |
| 11147132 | 60 mm | 50 pcs/pk |
| 11147133 | 90 mm | 50 pcs/pk |
| 11147136 | 142 mm | 50 pcs/pk |
5.0 μm pore size
| SKU | Diameter | Pack Quantity |
| 11147140 | 13 mm | 400 pcs/pk |
| 11147142 | 25 mm | 200 pcs/pk |
| 11147143 | 47 mm | 100 pcs/pk |
| 11147144 | 50 mm | 100 pcs/pk |
| 11147145 | 60 mm | 50 pcs/pk |
| 11147146 | 90 mm | 50 pcs/pk |
| 11147149 | 142 mm | 50 pcs/pk |
Download PDF Datasheet
Membrane rolls (bulk sheets) also available – Contact sales@hawach.com with width, length, and pore size.
Typical Applications
- HPLC & UHPLC: Mobile phase filtration, particulate removal, column protection
- Pharmaceutical Manufacturing: API synthesis, reaction mixture filtration, solvent purification
- Gas & Air Systems: Sterile venting, fermentation airflow control, environmental monitoring
- Chemical Industry: Strong acid/base clarification, organic synthesis solution filtration
Chemical Compatibility
Compatible: Acetonitrile, methanol, ethanol, acetone, THF, hexane, toluene, DMF, DCM, hydrocarbon oils, dilute strong acids & bases.
Not Recommended: Pure aqueous filtration (use hydrophilic PTFE), fuming strong oxidants at high temperature.
Manufacturing & Quality System
- ISO-controlled cleanroom production
- Per-batch bubble point & pore consistency validation
- Full lot traceability + COA documentation
- Stable global supply chain
- OEM private label & custom conversion available
FAQ
Can hydrophobic PTFE filter water?
Use hydrophilic PTFE for aqueous samples.
What solvents is it compatible with?
Most organic solvents including ACN, MeOH, THF, hexane, acetone, chlorinated solvents.
Is it suitable for HPLC mobile phase filtration?
Low extractable grade ensures stable baseline and minimal analytical interference.
Standard pore size for HPLC?
22 μm.
OEM / custom sizes available?
Yes – custom diameters, pore sizes, membrane rolls, private label packaging.
Free lab samples?
Yes – 13/25/47 mm discs for qualified labs.
Request Free Samples & Bulk Quotation
Free membrane samples (13/25/47 mm, any pore size) for lab evaluation. Bulk pricing, OEM customization, COA & batch reports available. Membrane rolls & custom dimensions available on request.
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