C18-Aqueous HPLC Columns

Descriptions of C18-Aqueous Liquid Chromatography Columns

C18-Aqueous HPLC Columns can endure 100% aqueous phase samples. With appropriate surface coverage and double end-capped technique, C18-Aqueous liquid chromatography columns have good compatibility with highly aqueous-based mobile phase and can provide a longer column lifetime. The stationary phase was specially made under double end-capped technique make it stable and special used for aqueous-based mobile phase

Advantage of C18 Aqueous HPLC columns

The most widely applied C18-Aqueous HPLC column in the analysis of the food industry
300 Å pore size available for the separation of macromolecular compounds
Highly specific surface area and mechanical strength ensured from high purity silica gel
Double end-capped for excellent peak shape when separation of polar, acidic, and basic compounds
Column peak shape and volume is perfect by spherical silica gel and good stability of batch to batch
Buffer systems, ion pair reagents do not need for analysis of drugs, combined chemicals, and LC-MS applications

Features

Increase column retention for polar and water soluble compounds
Fully end-capped stationary phase offers longer column lifetime
Less retentive than C18 Universal for non-polar compounds
No phase collapse and especially suitable for high aqueous based mobile phase
Excellent column peak shapes for basic and polar compounds ensured by the fully end-capped stationary phase

Application

Separation of metabolites and bio-molecules
Excellent column efficiency especially for applications of water soluble compounds which cannot be retained on the traditional C18 stationary phase
Drug degradation products Separation such as water-soluble vitamins, small molecules, amino acids, and small molecules of the nucleoside

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