C18 Alkaline HPLC Columns

Column: XChroma HPLC Column, C18-Alkaline, 4.6 ×250 mm, 5µm
Mobile Phase:
A: 0.5 mol/L KH2PO3(adjust pH to 3.5 with H3PO4): MeOH:water=10:30:60
B: 0.5 mol/L KH2PO3(adjust pH to 3.5 with H3PO4): MeOH:water=10:50:40
Flow Rate: 1.0 mL/min
Detector: 225nm
Temperature: 30°C
Injection Volume: 20μL



Description of C18-Alkaline C18 Analytical Columns

C18-Alkaline HPLC Column_3

C18-Alkaline is the new generation C18 HPLC chromatography columns. The c18 column composition of a column tube, a pressure cap, a ferrule (sealing ring), a sieve plate (filter), connectors, screws, etc. The C18-Alkaline HPLC Columns packed by hydrophilic functional groups bonded silica(high purity) so as to realize hydrophilic features. Hydrophilic groups are embedding into the ultra-pure silica to make it Hydrophilic. Hydrophilic groups replace most of the silanol groups to prevent the reaction between the basic compounds and silanol groups.

Selectivity of C18-Alkaline c18 analytical columns is different from traditional C18-Universal HPLC Columns, C18-Alkaline is a mixed stationary phase, which makes the filler resistant to strong alkali conditions of PH 12.5.

Advantage of C18 HPLC Chromatography Columns

Quicker Separation for similar samples
Fully bonding group and sorbents with wide selectivity for HPLC method development
Your HPLC method will be greatly developed or improved.
The column performs well and has exceptionally rugged USP phases
Column quality and reproducibility is stable from lot-to-lot

C18 Alkaline HPLC Columns


Quicker separation for similar compounds by one column
Excellent column peak shape especially for basic compounds
The stationary phase is mixed and with electrostatic and hydrophobic forces


1. Separation of alkaloids ingredients from Chinese medicine
2. Quickly separation of similar samples


Ordering Information

Item NoDescriptionPackage (pcs/pk)
SLHC18AL546150HPLC Column, C18-Alkaline, 5μm, 120Å, 4.6x150mm1
SLHC18AL546250HPLC Column, C18-Alkaline, 5μm, 120Å, 4.6x250mm1
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