Material: USP Class VI PP tube + HDPE cap
Sterility: Non-sterile / Gamma / E-beam / EO
Seal: Screw cap with sealing ring
Cleanliness: DNase/RNase-free, non-pyrogenic
Autoclavable: Yes
Availability: In Stock
Cryogenic Vials for Ultra-Low Temperature Sample Storage
Description
What Are Cryogenic Vials?
Cryogenic vials (cryovials) are specialized laboratory tubes designed for ultra-low temperature storage of biological samples, including -80°C freezers and liquid nitrogen environments (-196°C).
They are widely used in:
- Cell cryopreservation
- Biobanking
- Molecular biology
- Clinical and pharmaceutical laboratories
A cryogenic vial is engineered to ensure:
- Leak-proof sealing
- Chemical resistance
- Stability under extreme temperatures
Key Features of Hawach Cryogenic Vials
1. Ultra-Low Temperature Resistance
- Temperature range: -196°C to +121°C（Some models are-20°C）
- Suitable for cryogenic storage workflows
- Compatible with freezing and autoclaving processes
2. High-Purity USP Class VI Materials
- Tube: USP Class VI polypropylene (PP)
- Cap: high-density polyethylene (HDPE)
- Non-pyrogenic, DNase/RNase-free
- Low extractables for sensitive samples
3. Multiple Thread Designs
- External thread cryovials: Reduced risk of contamination
- Internal thread cryovials: Enhanced sealing performance
- Screw cap self-standing cryovials: High versatility
4. Secure Sealing System
- Sealing ring design（O-ring）
- Leak-proof performance during freezing & thawing
- Prevents contamination and sample loss
5. Self-Standing & Bottom Design
- Self-standing base for easy handling
- U-bottom & V-bottom options
Conical (V-bottom) design improves sample concentration and recovery efficiency.
6. Sterile & Non-Sterile Options
- Non-sterile (bulk supply)
- Gamma sterilized
- E-beam sterilized
- EO sterilized（Select Models）
7. Clear Graduation & Identification
- Printed scale marks（Select Models）
- Writing area for labeling
- Suitable for sample traceability
Product Series Overview
1. External Thread Cryogenic Vials (-196°C)
Non-Sterile
- 1 mL / 1.8 mL / 3.5 mL / 4.5 mL
- Self-standing & non-standing options
- U-bottom
- Packaging: up to 5000 pcs/carton
Sterile (Gamma)
- Same volume range
- Individually packed (50 pcs/bag)
- Cleanroom compatible
2. Internal Thread Cryogenic Vials (-196°C)
Non-Sterile
- 1 mL / 1.8 mL / 4.5 mL
- Self-standing options available
Sterile
- Gamma sterilized
- High-sealing performance
- Ideal for sensitive samples
3. Screw Cap Self-Standing Cryogenic Vials (-196°C)
Non-Sterile / Sterile
- 5 mL / 1 mL / 1.5 mL / 2 mL
- V-bottom
- Without scale mark
- Designed for compact storage
4. Standard Freezing Vials (-20°C Series)
Non-Sterile / Sterile
- 8 mL / 5 mL
- With or without sealing ring
- Designed for conventional freezing (not LN2)
General Specifications
- Material: USP Class VI PP tube + HDPE cap
- Temperature range:
- Cryogenic series: -196°C to +121°C
- Standard freezing series: -20°C to +121°C
- Sterility: Non-sterile / Gamma / E-beam / EO
- Seal: Screw cap with sealing ring
- Cleanliness: DNase/RNase-free, non-pyrogenic
- Autoclavable: Yes
Cryogenic Vials vs Centrifuge Tubes
| Feature | Cryogenic Vials | Centrifuge Tubes |
| Temperature | Up to -196°C | Typically ≥ -80°C |
| Sealing | Cryo leak-proof | Standard |
| Application | Long-term storage | Processing |
| Liquid nitrogen | Supported | Not recommended |
Applications
Cryopreservation
- Cell freezing
- Stem cell storage
- Primary cell preservation
Biobanking
- DNA/RNA storage
- Serum & plasma samples
- Long-term biological archives
Laboratory & Pharma
- Sample storage
- Vaccine research
- Drug development
Sample Storage & Biobanking
- Long-term biological sample storage
- Compound library management
- Reagent stock storage
These workflows are often combined with sterile sample bags for sample collection and media bottles for reagent storage.
Best Practice
- Prepare sample with cryoprotectant (e.g., DMSO)
- Fill cryogenic vial (avoid overfilling)
- Use controlled-rate freezing (~ -1°C/min)
- Store at -80°C
- Transfer to liquid nitrogen vapor phase
Vapor phase storage is recommended to reduce contamination risk.
FAQ
Are all cryogenic vials suitable for liquid nitrogen?
Only vials rated for -196°C should be used, preferably in vapor phase storage.
What is the difference between internal and external thread?
External thread reduces contamination risk, while internal thread provides stronger sealing.
Are the vials sterile?
Both sterile and non-sterile options are available, including gamma, E-beam and EO sterilization.
Can cryogenic vials be autoclaved?
Yes, they are autoclavable at 121°C.
What volumes are available?
From 0.5 mL up to 5 mL depending on design and series.
Order Information
External Thread Cryogenic Vials (–196°C)
| Non-Sterile | |||||||
| Cat# | Volume | Structure | Bottom | Sealing Ring | Scale | Temp Range | Packaging |
| 20061101 | 1 mL | Self-standing | U-bottom | Yes | Yes | -196~+121°C | 5000 (500pcs*10bags/Carton) |
| 20061102 | 1.8 mL | Self-standing | U-bottom | Yes | Yes | -196~+121°C | 5000 (500pcs*10bags/Carton) |
| 20061103 | 3.5 mL | Self-standing | U-bottom | Yes | Yes | -196~+121°C | 2000 (200pcs*10bags/Carton) |
| 20061104 | 4.5 mL | Self-standing | U-bottom | Yes | Yes | -196~+121°C | 2000 (200pcs*10bags/Carton) |
| 20061105 | 1.8 mL | Standard | U-bottom | Yes | Yes | -196~+121°C | 5000 (500pcs*10bags/Carton) |
| 20061106 | 3.5 mL | Standard | U-bottom | Yes | Yes | -196~+121°C | 2000 (200pcs*10bags/Carton) |
| 20061107 | 4.5 mL | Standard | U-bottom | Yes | Yes | -196~+121°C | 2000 (200pcs*10bags/Carton) |
| Sterile (Gamma) | |||||||
| Cat# | Volume | Structure | Bottom | Sealing Ring | Scale | Temp Range | Packaging |
| 20061201 | 1 mL | Self-standing | U-bottom | Yes | Yes | -196~+121°C | 5000 (50pcs*100bags/Carton) |
| 20061202 | 1.8 mL | Self-standing | U-bottom | Yes | Yes | -196~+121°C | 5000 (50pcs*100bags/Carton) |
| 20061203 | 3.5 mL | Self-standing | U-bottom | Yes | Yes | -196~+121°C | 2000 (50pcs*40bags/Carton) |
| 20061204 | 4.5 mL | Self-standing | U-bottom | Yes | Yes | -196~+121°C | 2000 (50pcs*40bags/Carton) |
| 20061205 | 1.8 mL | Standard | U-bottom | Yes | Yes | -196~+121°C | 5000 (50pcs*100bags/Carton) |
| 20061206 | 3.5 mL | Standard | U-bottom | Yes | Yes | -196~+121°C | 2000 (50pcs*40bags/Carton) |
| 20061207 | 4.5 mL | Standard | U-bottom | Yes | Yes | -196~+121°C | 2000 (50pcs*40bags/Carton) |
Internal Thread Cryogenic Vials (–196°C)
| Non-Sterile | |||||||
| Cat# | Volume | Structure | Bottom | Sealing Ring | Scale | Temp Range | Packaging |
| 20061301 | 1 mL | Self-standing | U-bottom | Yes | Yes | -196~+121°C | 5000 (500pcs*10bags/Carton) |
| 20061302 | 1.8 mL | Self-standing | U-bottom | Yes | Yes | -196~+121°C | 5000 (500pcs*10bags/Carton) |
| 20061303 | 4.5 mL | Self-standing | U-bottom | Yes | Yes | -196~+121°C | 2000 (200pcs*10bags/Carton) |
| 20061304 | 1.8 mL | Standard | U-bottom | Yes | Yes | -196~+121°C | 5000 (500pcs*10bags/Carton) |
| 20061305 | 4.5 mL | Standard | U-bottom | Yes | Yes | -196~+121°C | 2000 (200pcs*10bags/Carton) |
| Sterile (Gamma) | |||||||
| Cat# | Volume | Structure | Bottom | Sealing Ring | Scale | Temp Range | Packaging |
| 20061401 | 1 mL | Self-standing | U-bottom | Yes | Yes | -196~+121°C | 5000 (50pcs*100bags/Carton) |
| 20061402 | 1.8 mL | Self-standing | U-bottom | Yes | Yes | -196~+121°C | 5000 (50pcs*100bags/Carton) |
| 20061403 | 4.5 mL | Self-standing | U-bottom | Yes | Yes | -196~+121°C | 2000 (50pcs*40bags/Carton) |
| 20061404 | 1.8 mL | Standard | U-bottom | Yes | Yes | -196~+121°C | 5000 (50pcs*100bags/Carton) |
| 20061405 | 4.5 mL | Standard | U-bottom | Yes | Yes | -196~+121°C | 2000 (50pcs*40bags/Carton) |
Screw Cap Self-Standing Cryogenic Vials (–196°C)
| Non-Sterile | ||||||
| Cat# | Volume | Bottom | Sealing Ring | Scale | Temp Range | Packaging |
| 20061501 | 0.5 mL | V-bottom | Yes | No | -196~+121°C | 5000 (500pcs*10bags/Carton) |
| 20061502 | 1 mL | V-bottom | Yes | No | -196~+121°C | 5000 (500pcs*10bags/Carton) |
| 20061503 | 1.5 mL | V-bottom | Yes | No | -196~+121°C | 5000 (500pcs*10bags/Carton) |
| 20061504 | 2 mL | V-bottom | Yes | No | -196~+121°C | 5000 (500pcs*10bags/Carton) |
| Sterile (Gamma) | ||||||
| Cat# | Volume | Bottom | Sealing Ring | Scale | Temp Range | Packaging |
| 20061601 | 0.5 mL | V-bottom | Yes | No | -196~+121°C | 5000 (50pcs*100bags/Carton) |
| 20061602 | 1 mL | V-bottom | Yes | No | -196~+121°C | 5000 (50pcs*100bags/Carton) |
| 20061603 | 1.5 mL | V-bottom | Yes | No | -196~+121°C | 5000 (50pcs*100bags/Carton) |
| 20061604 | 2 mL | V-bottom | Yes | No | -196~+121°C | 5000 (50pcs*100bags/Carton) |
Cryogenic Vials (–20°C Storage Series)
| Non-Sterile | ||||||
| Cat# | Volume | Bottom | Sealing Ring | Scale | Temp Range | Packaging |
| 20061701 | 1.8 mL | V-bottom | No | Yes | -20~+121°C | 5000 (500pcs*10bags/Carton) |
| 20061702 | 1.8 mL | V-bottom | Yes | Yes | -20~+121°C | 5000 (500pcs*10bags/Carton) |
| 20061703 | 5 mL | V-bottom | No | Yes | -20~+121°C | 2000 (200pcs*10bags/Carton) |
| Sterile (EO) | ||||||
| Cat# | Volume | Bottom | Sealing Ring | Scale | Temp Range | Packaging |
| 20061802 | 1.8 mL | V-bottom | Yes | Yes | -20~+121°C | 5000 (500pcs*10bags/Carton) |
| 20061803 | 5 mL | V-bottom | No | Yes | -20~+121°C | 2000 (200pcs*10bags/Carton) |
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