Permanent Hydrophilic PTFE Membranes – Direct Replacement for Millipore, Whatman & Advantec
Why Labs Choose Hawach Hydrophilic PTFE Membranes
- No Pre-Wetting Required– Permanently hydrophilic PTFE allows direct aqueous solution filtration. Eliminates methanol/ethanol pre-wetting, saving time in HPLC and LC-MS workflows.
- HPLC & LC-MS Grade, Low Extractables– High-purity PTFE ensures stable baseline and minimal ghost peaks, ideal for sensitive analytical applications.
- Broad Chemical & pH Compatibility– Works from pH 1–14. Resistant to strong acids, bases, alcohols, ketones, esters, and most organic solvents.
- Low Protein Binding & High Sample Recovery– Smooth inert surface minimizes non-specific adsorption. Essential for biopharma, protein research, and enzyme assays.
- Autoclavable & Gamma Sterilization Compatible– Supports sterile filtration, microbial testing, and repeated laboratory use.
- Drop-in Replacement– Fits Millipore, Whatman, Advantec, Sartorius, Tisch, Sterlitech holders without workflow adjustment.
10-Second Selection Guide
| Sample Type | Recommended Pore Size | Why |
| Submicron particles, virus removal, ultracleaning | 0.1 μm | Highest retention, critical for sensitive LC-MS |
| Aqueous buffers, HPLC mobile phase, protein solutions | 0.22 μm | Removes bacteria & particulates, protects columns |
| Strong acids, organic solvents, general filtration | 0.45 μm | High flow rate, broad chemical tolerance |
| Coarse particles, prefiltration, dissolution testing | 1.0–5.0 μm | High throughput, extended filter life |
Core Technical Specifications
| Parameter | Specification |
| Membrane Material | Permanently hydrophilic PTFE (non-coating) |
| Pore Sizes | 0.1, 0.22, 0.45, 1.0, 5.0 μm |
| Disc Diameters | 13, 25, 47, 50, 60, 90, 142 mm |
| Wetting | Permanent, no alcohol pre-wetting required |
| Extractable Level | HPLC-grade, low extractable |
| Protein Binding | Low non-specific adsorption |
| pH Range | 1–14 |
| Max Temperature | 130°C continuous |
| Sterilization | Autoclavable, gamma irradiation |
| Compatible Brands | Millipore, Whatman, Advantec, Sartorius, Tisch, Sterlitech |
Complete SKU List – Hydrophilic PTFE Disc Filters
0.1 μm pore size
| SKU | Diameter | Pack Quantity |
| 11148209 | 13 mm | 400 pcs/pk |
| 11148210 | 25 mm | 200 pcs/pk |
| 11148211 | 47 mm | 100 pcs/pk |
| 11148212 | 90 mm | 50 pcs/pk |
0.22 μm pore size
| SKU | Diameter | Pack Quantity |
| 11147212 | 13 mm | 400 pcs/pk |
| 11147213 | 25 mm | 200 pcs/pk |
| 11147214 | 47 mm | 100 pcs/pk |
| 11147215 | 50 mm | 100 pcs/pk |
| 11147216 | 60 mm | 50 pcs/pk |
| 11147217 | 90 mm | 50 pcs/pk |
| 11147219 | 142 mm | 50 pcs/pk |
(0.45 μm, 1.0 μm, 5.0 μm follow the same format; membrane rolls also available.
Download PDF Datasheet
Common Laboratory Problems Solved
| Problem | Hawach Solution | Outcome |
| Hydrophobic PTFE needs pre-wetting | Permanent intrinsic hydrophilicity | Direct aqueous filtration, simplified workflow |
| Extractables interfere with HPLC/LC-MS | High-purity PTFE, low extractable | Stable baseline, reliable analytical results |
| Protein loss during filtration | Low protein-binding surface | Higher sample recovery, reduces waste |
| Poor chemical resistance | Full PTFE chemical resistance | One membrane handles strong acids, bases, and organics |
| Temporary coated hydrophilicity fails | Non-coating permanent modification | Long-term wetting stability, consistent batch performance |
Typical Laboratory Applications
- HPLC & LC-MS Analytical Labs:Mobile phase degassing, sample preparation, particle removal, column protection
- Pharmaceutical & Dissolution Testing:Dissolution medium filtration, QC sample preparation, regulatory compliance
- Biochemistry & Biopharma:Protein solution clarification, low-binding buffer filtration, enzyme assay preparation
- General Chemistry & Environmental Labs:Strong acid/base filtration, wastewater clarification, routine solution purification
Case Example:
A European biotech lab standardized on Hawach 0.22 μm PTFE membranes for LC-MS sample prep: 35% faster filtration, zero baseline drift, higher protein analyte recovery.
Chemical Compatibility
Compatible With:
Aqueous buffers, HPLC mobile phases, alcohols, acetonitrile, methanol, weak/strong acids and bases, most organic solvents
Avoid:
Fuming strong oxidizing agents under extreme heat, molten alkali metals, highly corrosive fluorinated reagents
OEM & Customization Services
- Custom membrane diameter / pore size available
- Private label & neutral OEM packaging
- Bulk wholesale pricing for distributors & institutions
- Membrane rolls in custom dimensions
- Full documentation: COA, batch analysis report, ISO compliance
Frequently Asked Questions
Q: Do I need to pre-wet with methanol?
A: No. Hawach hydrophilic PTFE is permanently wettable – filter aqueous solutions directly.
Q: What pore sizes are available?
A: 0.1 μm, 0.22 μm, 0.45 μm, 1.0 μm, 5.0 μm. Other sizes available on request.
Q: What disc diameters are available?
A: 13, 25, 47, 50, 60, 90, 142 mm. Membrane rolls also available.
Q: Are these membranes HPLC-grade?
A: Yes. Low extractables and controlled pore structure ensure stable baseline and minimal interference.
Q: Can these membranes be autoclaved?
A: Yes. Compatible with autoclaving (121°C, 20 min) and gamma sterilization.
Q: What pH range is supported?
A: Stable from pH 1 to 14.
Q: Are free samples available?
A: Yes. Free 13/25/47 mm discs for qualified labs – request via email with pore size and lab info.
Q: COA & batch documents?
A: Provided with every order for traceability and compliance.
Q: Do you sell membrane rolls, not just discs?
A: Yes. Contact us with your required width, length, and pore size.
Q: Are these membranes compatible with standard filtration holders?
A: Yes. Drop-in replacements for Millipore, Whatman, Advantec, Sartorius, Tisch, and Sterlitech holders.