Sample volume: ~0.4 mL (max fill line)
Pore sizes: 0.22 µm / 0.45 µm
Membrane options: MCE, PVDF, PTFE, Nylon
Material: Medical-grade polypropylene (no leachables)
Packaging: 100/pk, 10 pk/carton
Availability: In Stock
Sample volume: ~0.4 mL (max fill line)
Pore sizes: 0.22 µm / 0.45 µm
Membrane options: MCE, PVDF, PTFE, Nylon
Material: Medical-grade polypropylene (no leachables)
Packaging: 100/pk, 10 pk/carton
Availability: In Stock
Designed for fast, leachable-free filtration of small-volume samples directly into an autosampler vial. The syringeless filter vial integrates filtration and sample storage in one device — no syringe, no separate vial, no cap required. Reduces sample loss and preparation time by 70% compared to traditional syringe filtration methods.

Removes particulates, precipitates, and impurities from liquid samples before injection. Prevents column clogging, extends column life, and improves chromatographic peak shape.
Filters cell culture media, buffers, and reagents to ensure sterility. Ideal for microbiological experiments, cell culture, and protein solution preparation.
Compatible with organic solvents, acids, and bases. Choose chemically resistant PTFE membranes for aggressive solvents.
Filters water samples, air sampling extracts, beverages, and liquid food samples to remove particles prior to analysis.
Add sample to outer tube (max 0.4 mL), insert inner tube, and press down. Filtered liquid passes upward through membrane into inner tube. Ready for autosampler.
Fits autosamplers from Waters, Agilent, Shimadzu, and other major brands. Standard 1.5 mL vial dimensions.
Manufactured from medical-grade polypropylene. Tested with common solvents and LC-MS – no detectable leachables.
Assembled in a Class 100,000 (ISO 8) cleanroom to minimize particulate contamination.
Outer tube: 2 mL capacity, medical-grade polypropylene. Multiple uses possible after rinsing.
Inner tube: Push-cap design with pre-slit red silicone rubber / white PTFE sealing septa. Bottom membrane filter (0.22 or 0.45 µm) in various materials.
Assembly: Pressing inner tube forces sample through membrane; filtered liquid collects above. Small holes at top release air until locking ring seals.
| Membrane | Hydrophilicity | Pore Sizes | Best For | Chemical Compatibility |
| MCE (Mixed Cellulose Esters) | Hydrophilic | 0.22, 0.45 µm | Aqueous solutions, general laboratory filtration | Water, mild buffers |
| Hydrophilic PVDF | Hydrophilic | 0.22, 0.45 µm | Protein solutions, aqueous/organic mixtures | Low protein binding, good with mild solvents |
| Hydrophobic PTFE | Hydrophobic | 0.22, 0.45 µm | Organic solvents, air/gas filtration | Excellent for aggressive solvents (acetonitrile, methanol, hexane) |
| Hydrophilic PTFE | Hydrophilic | 0.22, 0.45 µm | Both aqueous and organic solutions | Universal compatibility, low extractables |
| Nylon | Hydrophilic | 0.22, 0.45 µm | General aqueous and organic samples | Good with many solvents, not for strong acids |
| Feature | Filter Vial (Syringeless) | Syringe Filter + Vial |
| Number of components | 1 integrated device (outer tube + inner tube) | Syringe, filter, vial, cap – 4 items |
| Sample loss | Minimal (direct filtration into final vial) | Higher (multiple transfers) |
| Time per sample | ~15-20 seconds | ~60 seconds or more |
| Cost per filtration | Lower (no separate consumables) | Higher |
| Best for | High-throughput labs, routine HPLC sample prep | Larger volumes (>1 mL) or specialized filter materials |
When to choose Filter Vial: Fast filtration with direct storage, minimal sample loss, reduced consumables.
When to choose Syringe Filter: Larger sample volumes (>1 mL) or when you already have an established workflow.
| Cat. No. | Membrane | Pore Size | Hydrophilicity | Septa | Packaging |
| 20165001 | MCE | 0.45 µm | Hydrophilic | Pre-slit red silicone/PTFE | 100/pk, 10 pk/carton |
| 20165002 | MCE | 0.22 µm | Hydrophilic | Pre-slit red silicone/PTFE | 100/pk, 10 pk/carton |
| 20165003 | Hydrophilic PVDF | 0.45 µm | Hydrophilic | Pre-slit red silicone/PTFE | 100/pk, 10 pk/carton |
| 20165004 | Hydrophilic PVDF | 0.22 µm | Hydrophilic | Pre-slit red silicone/PTFE | 100/pk, 10 pk/carton |
| 20165005 | Hydrophobic PTFE | 0.45 µm | Hydrophobic | Pre-slit red silicone/PTFE | 100/pk, 10 pk/carton |
| 20165006 | Hydrophobic PTFE | 0.22 µm | Hydrophobic | Pre-slit red silicone/PTFE | 100/pk, 10 pk/carton |
| 20165007 | Hydrophilic PTFE | 0.45 µm | Hydrophilic | Pre-slit red silicone/PTFE | 100/pk, 10 pk/carton |
| 20165008 | Hydrophilic PTFE | 0.22 µm | Hydrophilic | Pre-slit red silicone/PTFE | 100/pk, 10 pk/carton |
| 20165009 | Nylon | 0.45 µm | Hydrophilic | Pre-slit red silicone/PTFE | 100/pk, 10 pk/carton |
| 20165010 | Nylon | 0.22 µm | Hydrophilic | Pre-slit red silicone/PTFE | 100/pk, 10 pk/carton |
Standard 1.5 mL vial dimensions fit Waters, Agilent, Shimadzu, Thermo, PerkinElmer, and most HPLC/UHPLC autosamplers without adapters.
The outer tube has a fill line at approximately 0.4 mL. Do not exceed this line. After filtration, the inner tube contains about 0.2-0.3 mL of filtered sample – sufficient for most autosampler injections.
Designed for single use to avoid cross-contamination. However, the outer tube can be rinsed and reused for the same sample type if needed.
No. The medical-grade polypropylene has been tested with common HPLC solvents and LC-MS – no detectable leachables or extractables.
Hydrophobic PTFE repels water and is best for organic solvents. Hydrophilic PTFE wets with water and is suitable for both aqueous and organic samples.
Yes, 0.22 µm pore size removes bacteria. However, the device is not pre-sterilized; for sterile applications, please request gamma-sterilized versions (custom order).
Yes. OEM branding, custom membrane materials, and pre-sterilized options are available for volume orders. Contact us for details.

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