100 um Cell Strainer

High-Yield Filtration for Large Tissue Samples & Primary Cell Processing

The 100 µm cell strainer is designed for high-throughput and high-recovery cell filtration, making it ideal for processing large or partially dissociated tissue samples.

It allows rapid separation of cells from bulk tissue while minimizing cell loss, making it a preferred first-step filter in multi-stage cell preparation workflows.

Compared with smaller pore sizes, the 100 µm strainer prioritizes cell recovery and processing speed over fine filtration precision.

What Is a 100 µm Cell Strainer?

A 100 µm cell strainer is a sterile nylon mesh filter used to separate large tissue fragments and aggregates from cell suspensions during sample preparation.

Filtration Mechanism

During operation:

• Large tissue fragments and undigested material are retained on the mesh surface
• Cells and small aggregates pass through 100 µm openings
• High flow rate reduces processing time
• Minimal resistance prevents clogging in high-volume samples

This mechanism makes it suitable for early-stage tissue dissociation workflows.

Key Applications

• Primary tissue dissociation (organ and solid tissue samples)
• Stem cell isolation and processing
• Blood and large-volume cell suspensions
• Pre-filtration before finer strainers (70 µm / 40 µm)
• High-throughput biological sample preparation
• Bioprocessing and cell expansion workflows

Performance Advantages

• Maximizes cell recovery during initial filtration
• Fast processing of large or dense tissue samples
• Reduces clogging in downstream filtration steps
• Suitable for fragile or large cell populations
• High flow efficiency for bulk sample handling

100 µm vs Other Cell Strainer Sizes

• Compared with 70 µm Cell Strainer → higher throughput, less debris removal
• Compared with 40 µm Cell Strainer → significantly higher yield but lower purity

Best use case:
The 100 µm cell strainer is optimized for initial tissue processing where maximum recovery is more important than fine purification.

Workflow Position in Cell Preparation

In typical multi-step workflows:

• Step 1: 100 µm Cell Strainer → coarse tissue breakdown
• Step 2: 70 µm Cell Strainer → standard purification
• Step 3: 40 µm Cell Strainer → final single-cell refinement

The 100 µm strainer serves as the entry-level filtration stage for raw tissue samples.

Product Features

• High-strength nylon mesh for stable coarse filtration
• Medical-grade polypropylene frame for biocompatibility
• Green color-coded design for fast size identification
• Compatible with standard 50 mL centrifuge tubes
• Sterile, DNase/RNase-free, non-pyrogenic
• Individually packaged for contamination-free use

Product Specifications

• Product Name: 100 µm Cell Strainer
• Mesh Pore Size: 100 µm
• Mesh Material: Medical-grade nylon
• Housing Material: Polypropylene (PP)
• Color Code: Green
• Compatibility: Standard 50 mL centrifuge tubes
• Sterility: Sterile, DNase/RNase-free, non-pyrogenic
• Packaging: Individual sterile packaging

Why Choose Hawach Cell Strainers?

• Consistent mesh pore distribution for stable filtration performance
• High mechanical strength for large-volume tissue processing
• Low cell adhesion design to improve recovery efficiency
• Strict batch quality control for reproducible results
• Suitable for biomedical research, biopharma, and clinical labs
• Stable bulk supply with OEM customization available

FAQ

Why use a 100 µm cell strainer first?

Because it allows rapid removal of large tissue fragments while maximizing cell recovery, making it ideal as the first step in tissue dissociation.

What samples are suitable for 100 µm cell strainers?

It is commonly used for large tissue samples, primary organ dissociation, and high-cell-density suspensions.

Can it be used alone without other strainers?

Yes, but for higher purity applications it is often followed by 70 µm and 40 µm cell strainers for finer filtration.

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