Normal Phase Silica SPE Cartridges

Function Group: Si-OH
Particle size: 40-75 μm
Pore size: 70 Å
pore volume: 0.8cm³/g
Surface area: 480m²/g
Retention Mechanism: Unbonded silica particle that offers strong polar
selectivity at the mid PH conditions, silica surface silanols can be ionized


Description of Normal Phase Silica SPE Cartridges

Silicon Dioxide is one of the silica gel sorbents, it can extract polar analytes molecules from the non-polar liquid. So it is a kind of neutral sorbent. Normal Phase Silica SPE Cartridges can extract compounds to affect each other by becoming hydrogen bonds or polarity. The adsorbent in Silica is unbonded silica gel, which is generally regarded as the most polar adsorbent. The silanol on the surface can be partially dissociated to make it weakly acidic. Silica SPE cartridge is especially suitable for separating non-polar and weakly polar compounds with similar structures.


You can choose to customize your package.
The sample load and elution volume are just as expected.
Multi-imported sorbent to choose from.
Cartridge’s pore size is consistent between batches to guarantee a good flow rate.
The wide range of pH for your convenience.
Multi-imported sorbent choices.
Medical PP grade SPE cartridge with good chemical stability.

Features of

Normal phase silica SPE cartridges function group SI-OH, normally the particle size 40-75um and pore size can be 70Å, the sorbent surface area 480㎡/g.
Retention unbonded silica particle which can offer strong polar selectivity in the middle of pH conditions, also its normal phase SPE cartridge.
Retention mechanism: Unbonded silica particle that offers strong polar selectivity.


Analysis of the compounds of drugs and poisons and pollutants and the metabolites in biological matrices, also can analyst the bio-molecular like lipids, antibiotics, bile acids, and saccharides, to measure the preservative of cosmetics and skincare products.


Extracting Polar Compounds


Technical Data

Normal Phase Silica SPE Cartridges

Ordering Information

Item   No. SpecificationPackage (pcs/pk)
SLSPE1001SISilica, 40-75μm, 70Å, 100mg/3mL100
SLSPE2003SISilica, 40-75μm, 70Å, 200mg/3mL50
SLSPE5003SISilica, 40-75μm, 70Å, 500mg/3mL50
SLSPE5006SISilica, 40-75μm, 70Å, 500mg/6mL30
SLSPE1K6SISilica, 40-75μm, 70Å, 1g/6mL30
SLSPE1K12SISilica, 40-75μm, 70Å, 1g/12mL20
SLSPE2K12SISilica, 40-75μm, 70Å, 2g/12mL20
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