Screw Top Vials (Screw Cap Vials) with Caps and Septa

High-Performance Autosampler Vials for HPLC, GC and LC-MS

Complete laboratory vial system tailored for sample preparation, storage, and autosampler injection workflows. Hawach screw top vials come as an integrated system—vial, cap, and septa all in one—to ensure consistent sealing performance, lower contamination risk, and reliable, stable analytical results every time.

Our product line covers 2 mL autosampler vials, borosilicate glass storage vials, both clear and amber options, plus headspace-compatible formats—all designed to meet the needs of busy analytical laboratories.

Why Laboratories Use Screw Top Vial Systems

In analytical workflows, performance relies on the integrity of the entire system, not just individual components. That’s why labs prefer complete screw top vial systems:

• Stable sealing even during repeated autosampler injections
• Less evaporation and sample contamination
• Consistent compatibility with HPLC, GC, and LC-MS instruments
• Lower variability in analytical results

This product is purpose-built as a sealed system, combining vial, cap, and septa into one ready-to-use solution—no need to mix and match separate parts.

Product Specifications

• Volume range: 2 mL
• Thread standards: 8-425, 9-425
• Material: USP Type I borosilicate glass (glass screw top vials)
• Color options: Clear and amber
• Cap type: Screw thread, available in open-top or closed-top
• Septa options: PTFE/Silicone, PTFE/Silicone/PTFE, Silicone, Rubber
• Instrument compatibility: HPLC, GC, LC-MS autosamplers (screw top hplc vials)
• Cleanliness: Standard version is non-sterile; sterile, low-particulate, and low-endotoxin versions are available upon request

Thread Standard / Neck Size Selection

8mm (8-425) Screw Thread Vials

8mm (8-425) screw thread vials are the original, smaller opening auto-sampler vials. They are designed to work in a variety of auto-sampler requiring narrow neck vials. Clear and Amber vials with or without graduated writing area. Both pre-slit and non pre-slit caps are available.

8mm Assembled Caps and Septa for Screw Top Vial

Pre-assembled caps and septa reduce the chance of contamination of the septa during sample preparation. These caps are manufactured from high quality polypropylene and fit all of the 8mm screw top vials.

2ml Screw Top Vial(8-425) d1   11.6±0.25 d2   ≤8.0 d4   5.0±0.3 h1   32.0±0.50 d3   8.8±0.30 h3   ≈7.8 h5   1.6

9mm (9-425) Screw Thread Vials

9mm screw thread vials have a 9-425GPI thread, and the closure is dimensionally equivalent to 11mm crimp cap vials. This means that they can be used in any autosampler that uses 11mm crimp vials. 9mm screw caps have an advantage over 11mm crimp caps because 9mm screw caps can easily be applied and removed by hand and reused. Clear and Amber vials with or without graduated writing area. Both pre-slit and non pre-slit caps are available. All of Hawach vials are excellently fitted for auto-samplers.

9mm Assembled Caps and Septa

9-425 thread closures have the profile of a crimp or snap cap so are compatible with robotic auto-samplers. These caps are manufactured from high quality polypropylene and fit all 9mm screw cap vials.

2ml Screw Top Vial(9-425) d1   11.6±0.2 d2   8.1-8.5 d4   6.0±0.2 h1   32.0±0.5 d3   9.4±0.25 h3   7.3-7.9 h5   ≈1.2

How to Choose the Right Screw Top Vial

Step 1: Select by application

Step 2: Choose thread standard

9-425 (Modern standard)

This is the go-to standard for most modern analytical instruments, including Agilent, Waters, Thermo, and Shimadzu models. It’s recommended for HPLC and LC-MS work, offers great autosampler compatibility, and is the preferred choice for new method development—perfect for screw top hplc vials and 2 ml screw top vials.

8-425 (Legacy standard)

This standard is still used in older systems and for general storage applications. It works with legacy autosamplers and is a good fit for non-critical tasks, making it ideal for 2 ml screw top vials and 2 ml screw top vials & caps.

Septa Material Selection Guide

Septa Selection Guide

Final Selection Guide

For most laboratories, the correct configuration depends on application:

• LC-MS / HPLC -2 mL, 9-425, PTFE/Silicone/PTFE or PTFE/Silicone
• GC analysis- 2 mL, 9-425, PTFE/Silicone/PTFE
• Routine storage -2 mL, 8-425, Silicone or PTFE/Silicone
• High-sensitivity LC-MS -PTFE/Silicone/PTFE septa required
• Headspace -20 mL or 40 mL vial with Silicone septa

This section defines the recommended configuration for most laboratory workflows.

Key Advantages

• Pre-assembled caps and septa reduce contamination risk
• High chemical resistance with wide solvent compatibility
• Precision manufacturing ensures autosampler compatibility
• Strong sealing prevents evaporation and leakage
• Available in bulk supply and OEM customization

Applications

• HPLC and LC-MS sample preparation (screw top hplc vials, 2 ml screw top vials)
• Gas chromatography analysis
• Pharmaceutical quality control
• Environmental testing
• Sample storage and transport (2 ml screw top vials, glass screw top vials)
• Headspace analysis using 20 mL and 40 mL vials (glass screw top vials)

Ordering Information

We also offer custom configurations, OEM branding, and bulk pricing—just let us know what you need for your Screw Top Vials (2 ml screw top vials, 2 ml screw top vials & caps, glass screw top vials, screw top hplc vials).
Download PDF Datasheet

FAQ

What is a screw top vial used for?

It’s used for storing samples and running analyses in HPLC, GC, and LC-MS systems, with a secure threaded seal to keep samples safe.

What is the difference between screw cap vials and crimp vials?

Screw cap vials (Screw Top Vials) use threaded sealing, which is easy to handle—no extra tools needed. Crimp vials, on the other hand, require aluminum sealing tools to secure them.

Which vial is best for LC-MS?

A 2 mL 9-425 vial (2 ml screw top vials) with PTFE/Silicone/PTFE septa is our recommendation—it minimizes contamination, perfect for screw top hplc vials.

Are screw top vials compatible with autosamplers?

Absolutely. All standard 8-425 and 9-425 Screw Top Vials work with major autosampler systems, including those used for HPLC and LC-MS.

Can screw top vials be reused?

Yes, glass screw top vials can be reused, but you’ll need to clean them properly and validate their performance first—this depends on your specific application requirements.

Are sterile or low-particulate vials available?

Yes. We offer sterile, low-particulate, and low-endotoxin options on request—great for pharmaceutical QC and other sensitive analytical applications.