Basic Knowledge of Filter Membrane
Filtration of the sample is particularly important due to the precision of the chromatographic system and the accuracy requirements for the analysis of the results.
Filtration protects the chromatographic system and column, extending column life and improving data accuracy. Filtration eliminates pressure fluctuations caused by friction-generating particles and baseline fluctuations caused by irregular impurities. It is possible to eliminate interference with the detection system due to the presence of air bubbles. Therefore, a microporous membrane is usually used to filter the mobile phase, and a syringe filter is used to filter the sample.
Filter parameters and common sense
1. Filter life: The maximum operating time of the syringe filter under certain operating conditions. It depends on many factors, such as the nature of the filtrate, the operating temperature, and the choice of filter material.
2. Hydrophilic: The hydrophilic membrane usually has a special chemical layer so that the membrane can be wetted by water; hydrophilicity is a reference to the repulsive force of water. Hydrophobic filters rarely absorb water or do not absorb water at all.
3. Hydrophobicity: A property that describes a membrane or membrane material that is not readily soluble in water. Hydrophobic filter membrane rarely absorb water or do not absorb water at all.